Past Research:

Doctoral Studies (University of Western Ontario, London, Ontario)
My previous research has been directed towards improving orthopaedic treatment options for the distal radioulnar joint (DRUJ), which is a forearm joint near the wrist responsible for forearm rotation (pronation and supination).  I was involved in designing a replacement implant for the distal ulna, and evaluating this implant using in-vitro methods including joint kinematics and joint force measurements.  In vitro joint kinematic data were collected from cadaveric specimens using a custom forearm simulator and an electromagnetic tracking device.  Electromyography data of the forearm muscles was used to produce computer controlled unassisted forearm rotation in the cadaveric specimens.  Joint loading information in the DRUJ was also obtained via an instrumented implant system.

Post-doctoral Studies (University of Calgary, Calgary, Alberta)

A method of noninvasively detecting arthritis was explored using gadolinium enhancement and magnetic resonance (MR) imaging. With the onset of arthritis, many molecules within cartilage begin to disappear or degrade. These molecules carry an associated charge, leaving a net charge when they are degraded. A magnetic molecule (gadolinium), when exposed to arthritic tissue, is inversely attracted to this charge deficit, resulting in a high concentration of gadolinium in degraded areas of cartilage. This will subsequently generate a high intensity region on an MR image. This possible technique of clinically detecting arthritis in its earlier stages was explored in an animal model of osteoarthritis.

Dr. Karen Gordon


MR image showing cartilage tear (arrows).

Questions about this website? Contact: Mary Leunissen

The function of the distal radioulnar joint, involving the distal ends of the radius and ulna.

This work was used in developing an implant for the distal ulna. This implant is now available on international markets through Wright Medical Technologies (Arlington TN).

The E-centrix ulnar replacement system from Wright Medical Technologies (left), and an illustration of the implant in the distal radioulnar joint (right).